A Brief History of Cannabis Medicine

For thousands of years, cultures around the world utilized the cannabis plant as food, fiber and medicine. Cannabis appears in the first materia medica ever written. The earliest Chinese pharmacoepoia, Shen Nung’s Pen Ts’ao Ching (Divine Husbandman’s Classic of Materia Medica), was passed on by oral tradition and dates back to between 2637 and 2737 B.C.E. Nung is considered the Chinese god of agriculture and possibly the mythical Second Emperor of China. Researchers date the oldest written compilation that still survives documenting these Chinese oral medical traditions to between 300 ...
More

STUDY: Tincture of Cannabis to treat “Cannabis Dependency”?

Last month, the Journal of American Medicine (JAMA) Internal Medicine released a study claiming Nabiximols successfully “reduced illicit cannabis use in patients with cannabis dependence.” The study was poorly designed and meaningless, and the subsequent article was short on logic and facts. Let’s review them. Nabiximols, or GW Pharmaceuticals’ Sativex, is a standardized cannabis tincture with an equal dose of CBD and THC. It is essentially a whole plant cannabis extract. Nabiximols is replacing “illicit”, or illegal,  cannabis use only by the default of it being in the early stages of FDA...
More

Cannabis, the Constitution and States Rights

The change in the legal status of the cannabis plant has been a mixed blessing. The industry is now entering the arena of dynamic market capitalism despite many of its pioneers still serving lengthy prison sentences and many seriously ill patients still going without.   Too often these new corporate growers don’t have the same passion and spiritual attachment to the plant that the former outlaws who grew it did. This has many implications for both business and government. We need to avoid the negative baggage of entrepreneurship with its crony capitalism, cut-throat competition, and l...
More

Why Do We Even Have Drug Schedules?

Prior to 1970 there was no such thing as a federal drug schedule. This concept was enacted as part of the Controlled Substances Act (CSA) and President Nixon’s War on Drugs. The CSA was a politically driven law, not a medically or scientifically generated piece of regulation. The CSA created five schedules allegedly based on medical use and abuse potential. Although cannabis has a 4,000-year history as a human medication, under federal law it is placed in Schedule I meaning it has no accepted medical use and a high potential for abuse. Marinol, synthetic THC, was approved by the FDA as a ...
More

Dispensaries v. Pharmacies: Why Are They Regulated So Differently?

In several court decisions, the California Supreme Court has determined that a doctor’s recommendation for the medical use of cannabis is, for all intents and purposes, the equivalent of a prescription. Since that is the case, that determination should have application to dispensaries. Photo: Cannabis Museum, Ohio Historically from the 1850s until 1942, cannabis-containing prescriptions and patent medicines were available in pharmacies. One needs to ask why dispensaries and pharmacies are not treated under the same regulations today. Dispensaries ought to have a legal obligation to ...
More

Painless: The Case of Too Much Anandamide

When it comes to pain it looks like you can’t have too much Anandamide. Anandamide, aka “the bliss molecule”, or N-arachidonoylethanolamine (AEA) is an endogenous cannabinoid produced by the human body that binds to the endocannabinoid system similar to plant-derived THC. Anandamide, the "Bliss Molecule" Recently an article appeared in the British Journal of Anesthesia that discussed an unusual case of a woman who felt little or no pain. When the case came to the attention of researchers, what they found provides us with more insight regarding the analgesic and anxiolytic effects not o...
More

A Brief History of Medical Cannabis and Cannabinoids in the U.S.

The Ayurvedic Medicine Materia Medica Since the late 1940s and early 1950s, both state and federal entities have assiduously avoided treating cannabis as the medicine it has been for over 4,000 years. Cannabis has been recognized as a medicine since at least 2637 B.C.E. when it was included in the first known pharmacopoeia, the Ping Ts’ao Ching, alleged to be written by the second Emperor of China, Shen Neng. Cannabis has appeared in all subsequent major pharmacopoeias including an Ayurvedic Medicine Materia Medica, dated from between 1100 B.C.E. and 1700 B.C.E., as well as the Ebers Papy...
More

Who We Are

The AACM is a clinical medicine, scientific association. Its members are clinicians and researchers active in the field of endogenous, plant-derived and synthetic cannabinoids and those who support the medical use of cannabinoids. It is the gold standard for the education and dissemination of clinically relevant information in the emerging field of cannabinoid and endocannabinoid medicine. Our focus is on the application of clinical and physiological studies of cannabinoids and the endocannabinoid system. We provide professional and legal support in the field of cannabinoid medicine. We ed...
More

The Systemic Lack of Education About the Endocannabinoid System Leads to Widespread Ignorance About Cannabis

by David Bearman, M.D. The lack of education from grade school through grad school and medical school regarding cannabis, cannabinoids and the endocannabinoid system (ECS) is directly a result of bad policy. Up and down this is due to the government dealing with many psychoactive substances on a criminal justice basis not as medicine and not following the science.  Much of education problem can be traced to our medical schools. The majority of U.S medical schools are not even addressing the ECS, arguably the largest neurotransmitter system in the human brain, let alone the med...
More

Quality vs. Junk Science: Read the Study, Not Just the Headline

The United States is in an epidemic; there are too many people rejecting real science while embracing junk. This is not an isolated phenomenon, it applies to global warming, disease prevention and policy toward substance use and abuse. Just because a study has been done doesn’t mean it is a well-designed, valid study. One needs to look beyond the alleged results and look at the design. We need to look at the results with a critical eye toward such matters as study design and raw data, and how the data has been integrated. When you read a new headlines about a study ask questions. Is i...
More